α-Amylase Inhibitory Triterpene from Abrus precatorius Leaves

Abrus precatorius Linn leaves in wistar rats

Abrus precatorius leaves have been used in traditional medicine for the treatment of a variety of diseases including cough, malaria and infertility in women. It has also been shown to have various useful pharmacological effects. In this study, oral acute toxicity of the aqueous, 70% methanol, Petroleum ether and Acetone extracts were investigated. The graphical method of Miller and Tainter was ...

Antitrypanosomal isoflavan quinones from Abrus precatorius.

Human African trypanosomiasis is a neglected tropical disease in sub Saharan Africa that is fatal if left untreated. In a search for new natural products with antitrypanosomal activity, we recently identified abruquinones B and I from Abrus precatorius as potent in vitro trypanocidal compounds with high selectivity indices. To obtain sufficient compound for in vivo efficacy tests in mice, a sec...

Anticonvulsant Activity of Ethanolic Extract of Abrus Precatorius Leaves

Abrus precatorius which is commonly called as Indian licorice has been used for many centuries by traditional healers of Tanzania for the treatment of convulsions. The present work has been carried out to evaluate the anticonvulsant activity of the ethanolic extract (EE) of A. precatorius leaves against Pentylenetetrazole (PTZ), Picrotoxin and Maximal electroshock (MES) induced convulsions at t...

Plant Growth Inhibitor from Abrus precatorius Seeds.

Abrus precatorius poisoning.

Sir, This is with reference to Vaidya et al1 correspondence on the case report “Poisoning due to white seed variety of Abrus precatorius” by Pillay et al.2 Vaidya et al have noted that the use of broad spectrum antibiotics like meropenem and ceftriaxone by Pillay et al has no evidence based rationale. However, they themselves have mentioned the antidotal therapy for Abrus poisoning which has no...